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Great end to the year! https://rohatgilab.stanford.edu/news/2017/11/4/chandni-has-joined-us-as-a-rotation-student monthly 0.5 2018-03-26 https://rohatgilab.stanford.edu/news/2017/9/27/giovanni-successfully-defends-his-thesis monthly 0.5 2017-10-04 https://rohatgilab.stanford.edu/news/2017/9/27/ria-joins-23andme monthly 0.5 2017-10-09 https://rohatgilab.stanford.edu/news/2017/10/3/maia-passes-her-qualifying-exams monthly 0.5 2017-10-04 https://rohatgilab.stanford.edu/news/2017/9/27/raj-is-awarded-tenure-by-the-department-of-biochemistry monthly 0.5 2018-03-26 https://rohatgilab.stanford.edu/home daily 1.0 2025-02-28 https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/1522352671643-SHGQFKH8LFA8RCCTHG09/Screen+Shot+2018-03-29+at+12.42.39+PM.png Home https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/1625800534450-DBG70BDIOWP8CG1ARM84/for+lab+website_2021_slide+1-01.png Home https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/1625800536167-UHG6BGUI5ZUZOR0NB41L/for+lab+website_2021_slide+2-01.png Home https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/1625853207156-YENW6MVHKTEOQZ6NN3LY/for+lab+website_2021_slide+3-01-01.png Home https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/1625868837164-H8VQNII8N3PV818LENNW/for+lab+website_2021_slide+4-01.png Home https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/1625868836205-LYIBNI9FIZKIU0NM0YZD/for+lab+website_2021_slide+5-01.png Home https://rohatgilab.stanford.edu/blog-example-heights daily 0.75 2025-05-09 https://rohatgilab.stanford.edu/blog-example-heights/2017/fusce-sit-amet-massa-turpis-xpdmy monthly 0.5 2016-07-25 https://rohatgilab.stanford.edu/blog-example-heights/2016/aliquam-sit-amet-ullamcorper-tellus-kan8f monthly 0.5 2016-07-25 https://rohatgilab.stanford.edu/blog-example-heights/2016/aliquam-eu-posuere-at-semper-sed-elit-5ma2p monthly 0.5 2016-07-25 https://rohatgilab.stanford.edu/blog-example-heights/2016/eget-convallis-eros-metus-non-neque-6tw4w monthly 0.5 2016-07-25 https://rohatgilab.stanford.edu/blog-example-heights/2016/duis-suscipit-neque-quis-rhoncus-interdum-sfx63 monthly 0.5 2016-07-25 https://rohatgilab.stanford.edu/blog-example-heights/2016/fusce-rhoncus-vulputate-ex-eget-lacinia-orci-pmnnp monthly 0.5 2016-07-25 https://rohatgilab.stanford.edu/blog-example-heights/2016/curabitur-porttitor-auctor-diam-auctor-sagittis-lmaae monthly 0.5 2016-07-25 https://rohatgilab.stanford.edu/blog-example-heights/2016/morbi-scelerisque-leo-in-porta-lobortis-rkwyt monthly 0.5 2016-07-25 https://rohatgilab.stanford.edu/album-example-heights daily 0.75 2025-05-09 https://rohatgilab.stanford.edu/events-example-heights daily 0.75 2025-05-09 https://rohatgilab.stanford.edu/events-example-heights/2016/example-event-k9b74 monthly 0.5 2016-07-25 https://rohatgilab.stanford.edu/about daily 0.75 2018-03-26 https://rohatgilab.stanford.edu/contactus daily 0.75 2024-08-09 https://rohatgilab.stanford.edu/photos daily 0.75 2026-01-16 https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/78fcf094-6128-49a0-98b2-3cf6fe4709bc/Screenshot+2026-01-16+at+11.59.58%E2%80%AFAM.png photos - Make it stand out The Rohatgi Lab takes our annual white elephant very seriously — and good luck to anyone who unwraps a gift that might look like a dog toy! https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/04ec2c7f-c50f-4204-a314-858d70a2991b/IMG_0830.jpg photos - Make it stand out Raj took the lab out to his favorite ice cream spot in Santa Cruz! Oct 2025 https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/985dccf9-7b1c-432d-9de1-fb4e32ba21fb/IMG_0807-1.png photos - Make it stand out Shivali caught in the act — everyone was so excited to see her work at retreat! (2025) https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/a1b6be0a-5d6e-4e23-819d-d55e988c7444/IMG_0795.jpg photos - Make it stand out Mandi and Yuki at Yuki’s poster enjoying some boba! Another fun Biochemistry department retreat (2025) https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/64cafa78-1e68-4b08-95dd-9564aaa84c42/IMG_4790.png photos - Make it stand out Katie and Summer present Mandi’s awesome poster at the 2024 Biochemistry retreat! https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/7914aeec-bbe8-4053-8562-53b4f81649c0/IMG_4795.png photos - Make it stand out Yuki and one of our rotation students, Summer, enjoy S’mores! https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/dc33502c-faf7-4bf3-98aa-10e9db18333f/IMG_1742.jpg photos - Make it stand out Celebrating Raj's promotion! https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/1668315704007-Q4ZN0TKXII0SPTGUH26E/IMG_1529.jpg photos https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/1668315635072-B7SZME92HG8RWWUX5WE9/IMG_1527.jpg photos https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/1668315546265-TTSZN3DEVWHG5SBFAP01/IMG_1511.jpg photos https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/1668315488648-I3IVXVKHL9KWHUKQHRPZ/IMG_1486.jpg photos https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/1668315435490-HPGF811VI56DHSIECGKA/Ano%2BNuevo%2Bvisit_2022.jpg photos https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/1624816704257-6VR76VPEBS9671RZ9LP4/Image+from+iOS.jpg photos - Farewell party for Sara Frigui (May 2021) https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/1571349667919-S3DM39GA80HMZVWOIVXB/Rohatgi+Lab+hike+1.jpg photos - Hike at Wilder Ranch https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/1571349687628-FHX3LL9P70WESJ6KOA7Z/Rohatgi+Lab+hike+2.jpg photos - Wilder Ranch - take 2 https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/1535727579278-1C9O4R5GIRII0M26IWT5/IMG_2425.jpg photos - We escaped! :) https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/1532467691259-PILUKQKL5IPOLQYXDVK3/Screen+Shot+2018-07-24+at+2.26.54+PM.png photos - Farewell party for a few Rohatgi lab members https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/1532467685344-HHLF9G5CKB0KEAP9TX49/Screen+Shot+2018-07-24+at+2.27.25+PM.png photos - Giovanni's graduation. Congratulations!! https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/1509815424995-WEXD100H9BH7EK3DQTWG/IMG_5194.JPG photos - How well does Giovanni know Raj? -Biochemistry Retreat 2017 Question: What does Raj do in his free time? Giovanni: Fantasy football Raj: Sleep and Read about sports https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/1509815425918-PUMQWMDPB0O6RB53JUWJ/IMG_5196.JPG photos - Happy Birthday Giovanni! https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/1507145741171-NBR413O8EOLB4A5U728O/Celebrating_giovannis_defense.jpg photos - Celebrating Giovanni's Thesis Defense! https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/1505948814269-V539G9DK7RP7B6POVZ69/Summer_party1.jpg photos - Party at Raj's house- Summer 2017 https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/1505948897866-8QYEFA4WF14LLIVG9VHZ/Birthday.jpeg photos - Ganesh's daughter's 1st birthday! https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/1507145803140-QVCKWNAJITTCOL93D4LH/Bhaven%27s+birthday.JPG photos - Happy birthday Bhaven! https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/1505948813400-SCGB6IAAG5RPWV4E4FPZ/eamon_visits.jpeg photos - Eamon Byrne visits from the Siebold lab in the UK! https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/1507145756483-AETKK90HGYKFILAIGHOH/Broders_30th_bday2.JPG photos - Happy birthday Broder! https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/1507145792516-IAWCE8U6OHZ3BM0TNEHC/Broders_30th_bday1.JPG photos - Say cheese!!!! https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/1507588022090-Q7HKKDJJ8GP048U391LC/bhavens_graduation.JPG photos - Bhaven's graduation https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/1507145766584-4T33SWTX5BBIC3T3NMXS/lab_meets_diya.JPG photos - Lab meets Diya! https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/1507145782455-3PNL2A490TTVLGRUII8H/trip_to_monterey.JPG photos - Trip to Monterey- Summer 2015 https://rohatgilab.stanford.edu/alumni daily 0.75 2026-06-09 https://rohatgilab.stanford.edu/join-us daily 0.75 2024-08-08 https://rohatgilab.stanford.edu/areas-of-focus daily 0.75 2021-07-09 https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/1523378805152-U9DBJBADC3BSHHJ4UUU6/Screen+Shot+2018-04-10+at+9.45.53+AM.png areas of focus https://rohatgilab.stanford.edu/strategies daily 0.75 2021-07-09 https://rohatgilab.stanford.edu/publications-1 daily 0.75 2026-07-23 https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/ddd0c032-d666-421a-8c2a-955b66fd7038/403+3847_rohatgi_cover_nature_genetics+2.jpg publications - Make it stand out In colon cancer, beta-catenin regulates its own destruction, achieving a “just-right” level of signaling that drives cancer growth (auto-regulation via the “ouroboros mechanism”). https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/fa7addee-08de-46de-ad37-e0a257c9c35a/2026-04-08+12.51.04.jpg publications - Make it stand out The MEGF8–MOSMO–MGRN1 (MMM) complex operates like a fishing rig to ubiquitylate cell surface receptors. https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/a4782c5a-1b5b-41b4-b7f8-5d9b7300dbb2/Picture1.jpg publications - Make it stand out Several HSP90B1 client receptors are regulated by CCDC134. https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/789e79e0-eb0e-442c-891a-ef3103607042/Nature+2025.jpg publications - Make it stand out Model for regulated GRP94 N-glycosylation. https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/3f8a81a7-cc99-48a1-9986-54cb6c854758/sciadv.2025.11.issue-8.largecover.jpg publications - Make it stand out Artistic rendering of a universal prion-based mechanism for ionic strength sensing (represented by gauge) inside animal cells. https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/e944e712-e657-44f7-8bc9-684f1b43ba57/Science+2024.jpg publications - Make it stand out The pre-N segment tethers HSP90B1 during its translation, translocation, and folding to translocon-associated OST-A through an interaction between the SRT pseudosubstrate site and the STT3A sequon binding site. https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/7acf0419-b18d-442a-a072-5a9e91950ee9/sciadv.adh1609-f1.jpg publications - Make it stand out PTCH1 and the energetics of cholesterol transport—the indirect pathway. https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/bf1cd041-d5b4-4463-bba3-cb6c489f02e3/bi920273.f6.gif publications - Make it stand out Models for how PTCH inhibits SMO. https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/78107161-d0e9-4900-a520-81d5cc02b561/Sci+Adv+2022.jpg publications - Make it stand out Two models for the regulation of SMO signaling by PTCH1. In model 1, PTCH1 depletes the membrane of accessible cholesterol, indirectly inhibiting SMO, while in model 2, PTCH1 directly removes cholesterol from the SMO CRD. https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/1624751117535-973TLPMAVSJX9ZAE70Z3/emmm.v12.11.cover.jpg publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/1624751499880-40MTT5SD979AQL4XIRO3/1238.png publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/1575405144102-8MHLA2L234BPBMZCWQPO/Maia%27s+eLife+paper_poster.jpg publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/1575399506980-R1CJMUJI4B204X19N33C/ScienceSignaling.jpg publications - Make it stand out The Hedgehog signal transducer Smoothened (red) localized to the cilia of cells in the embryonic mouse spinal cord. https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/1575399268520-JXY2VXA1HQ6P59ZJ89VN/DevCell.jpg publications - Make it stand out An artistic depiction of the fluorescence-activated cell sorting (FACS) method used in conjunction with CRISPR-based genome-wide screens to identify positive (green hedgehogs) and negative (red hedgehogs) regulators of the Hedgehog signaling pathway. https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/1624750818086-0SXUZ6YDN370HOKPTZ72/2015+Dev+Cell_cover.jpg publications - Make it stand out Three-dimensional rendering of Smoothened protein presence in primary cilia lining the ventral spinal cord. Notch signaling facilitates Smoothened entry into primary cilia and, thereby, the potency of Sonic hedgehog in specifying distinct neural progenitor fates. https://rohatgilab.stanford.edu/currentmembers daily 0.75 2026-07-23 https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/e05ffc53-0e79-402f-951c-10e5754407e3/Rohatgi%2Bheadshot.jpg current members - Rajat Rohatgi Professor, biochemistry and medicine https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/4528e72a-705e-49c4-b547-85bc361db0f2/SR+Headshot+copy.jpg current members - Shivali Rawat Life science research professional https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/bf16eef0-9a4b-4e03-bbd5-6ddaf422e531/IMG_1304%5B52%5D.png current members - Yuki Yoshida Research associate https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/5662a184-576e-4fff-8d2b-75cf4d54c693/delongphoto%5B26%5D.png current members - Katie DeLong Graduate student, mcp https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/ea3954fe-cd06-4228-ae18-40efb0e64c06/1666327181389.jpg current members - Parijat Sarkar postdoctoral scholar https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/25e20580-b528-4ce3-9fe9-a51a77752b16/Mandi.jpg current members - Mandi Ma Postdoctoral scholar https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/aacf24d8-b0d9-4235-a983-959d9ca4ab74/Maia.jpg current members - Maia Kinnebrew Postdoctoral scholar https://images.squarespace-cdn.com/content/v1/59bc5c1fd7bdce156a4c688f/1be0fd11-c305-48ab-8593-44be0840f9bd/Ganesh.jpg current members - Ganesh Pusapati Senior research scientist